《名医堂》| 备孕、孕期、儿童成长,维生素D到底怎么补?四位三甲医院专家给出答案
2026-07-20 19:24:40
我国超过90%的成年人维生素D不足[1],超过70%青春期儿童维生素D缺乏[2]。两个人群,同一个缺口。
· 为何超过90%的育龄女性维生素D不足?问题出在哪?
· 备孕期维生素D偏低,补充方案和常规预防有何不同?
· 肥胖或35岁以上备孕,为何需要常规剂量2到3倍的补充?
· 如何加速消耗孩子体内储备的维生素D?
· 维生素D2和D3有什么区别?AD同补还是单独补D3就够了?
· 给孩子选维生素D,滴剂、胶囊、片剂哪种更适合?
· 每天400IU预防剂量长期服用,离中毒剂量到底有多远?
[1] 中华医学会骨质疏松和骨矿盐疾病分会. 维生素D及其类似物的临床应用共识(2025版)[J]. 中华骨质疏松和骨矿盐疾病杂志, 2025, 18(5): 497-517.
[2] Pang X, Zhang Q, Zhai Y, et al. Prevalence of micronutrient deficiencies in children and adolescents aged 3-17 years — 14 PLADs, China, 2019-2021[J]. China CDC Wkly, 2025, 7(23): 517-522.
[3] Maugeri A, Barchitta M, Favara G, et al. The Role of Diet in Women of Childbearing Age: Current Evidence Supporting Nutritional Recommendations. Nutrients. 2025;17(22):3505.
[4] Wei R, Christakos S. Mechanisms Underlying the Regulation of Innate and Adaptive Immunity by Vitamin D. Nutrients. 2015;7(10):8251-60.
[5] Dragomir RE, Toader OD, Gheoca Mutu DE, et al. The Key Role of Vitamin D in Female Reproductive Health: A Narrative Review. Cureus. 2024;16(7):e65560.
[6] Leonardi R, Mattia C, Decembrino N, et al. The Critical Role of Vitamin D Supplementation for Skeletal and Neurodevelopmental Outcomes in Preterm Neonates. Nutrients. 2025;17(8):1381.
[7] Xiao P, Cheng H, Wang L, et al. Relationships for vitamin D with childhood height growth velocity and low bone mineral density risk. Front Nutr. 2023;10:1081896.
[8] Pourshahidi LK. Vitamin D and obesity: current perspectives and future directions. Proc Nutr Soc. 2015 May;74(2):115-24.
[9] Chalcraft JR, Cardinal LM, Wechsler PJ, et al. Vitamin D Synthesis Following a Single Bout of Sun Exposure in Older and Younger Men and Women. Nutrients. 2020;12(8):2237.
[10] Sourbron J, Auvin S, Cabral-Lim L, et al. Vitamin D prophylaxis in persons with epilepsy? Epilepsia. 2024 Sep;65(9):2567-2579.
[11] Chaudhuri JR, Mridula KR, Rathnakishore C, Balaraju B, Bandaru VS. Association of 25-Hydroxyvitamin D Deficiency in Pediatric Epileptic Patients. Iran J Child Neurol. 2017 Spring;11(2):48-56
[12] Golden NH, Abrams SA; Committee on Nutrition. Optimizing bone health in children and adolescents. Pediatrics. 2014;134(4):e1229-43.
[13] Arshad R, Sameen A, Murtaza MA, et al. Impact of vitamin D on maternal and fetal health: A review. Food Sci Nutr. 2022;10(10):3230-3240.
[14] Mahon P, Harvey N, Crozier S, et al. Low maternal vitamin D status and fetal bone development: cohort study. J Bone Miner Res. 2010;25(1):14-9.
[15] Heo JS, Ahn YM, Kim AE, Shin SM. Breastfeeding and vitamin D. Clin Exp Pediatr. 2022 Sep;65(9):418-429.
[16] Winzenberg T, Powell S, Shaw KA, et al. Effects of vitamin D supplementation on bone density in healthy children: systematic review and meta-analysis. BMJ. 2011 Jan 25;342:c7254.

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